Unveiling Mast Cell & Fibromyalgia Connection

Fibromyalgia comes with many comorbid conditions that can be directly affected by mast cell reactions. Some conditions can include bladder pain syndrome/interstitial cystitis (BPS/IC), gastrointestinal symptoms (GI), neurologic inflammation and pain, and mast cell dysfunction and disorders.

Mast cells in the skin are the guardians that quickly react to stimuli that disturb a person’s homeostasis. Mast Cells (MCs) are found in the mucous membranes of the respiratory along with the digestive tract along with submucosa and connective tissue adjacent to the conjunctiva and skin. MCs are part of the pathogenesis of allergic, auto inflammatory and cancer disease as well.

Since our skin is the largest organ of the body that protects us from external physical, chemical, along with microbiological factors. MCs are one of the representatives that react first in the immune response. MCs are part of both the innate and adaptive immune responses.

Neurological Inflammation & Pain

Thalamic mast cells contribute to inflammation and pain, by releasing neuro-sensitizing molecules that include histamine, IL-1β, IL-6 and TNF, as well as calcitonin-gene related peptide (CGRP), HK-1 and SP. These molecules could either stimulate thalamic nociceptive neurons directly, or via stimulation of microglia in the diencephalon. As a result, inhibiting mast cell stimulation could be used as a novel approach for reducing pain and the symptoms of FMS,” states the PubMed website.

Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC)

Mast cells involved in allergic reactions are distributed throughout the blood vessels, lymph glands, and nerves of the bladder, as well as the bladder smooth muscle and mucosa. Mast cells activated by the involvement of neurological, immune, and endocrine factors are thought to play a central role in the progression of IC/BPS in many patients,” states the International Neurology Journal website.

Gastrointestinal Pain & Inflammation

Diet modification in patients with fibromyalgia by specific histamine release test improves certain clinical parameters related to the symptoms of the digestive sphere, compared to the control group. Our work opens a possible way of non-pharmacological treatment to improve some symptoms of this very prevalent disease,” states the Rheumatologia website.

The identification of the DAO enzyme deficiency in FMS patients has made it obvious that histamine and mast cell reactions directly correlate for a lot of the sub symptoms of Fibromyalgia and it’s associated pain.

DAO deficiency can create a histamine intolerance in FM patients. Photo cred:meineresterampe/Pixabay

Associations between fibromyalgia symptoms and candidate variants of the AOC1 gene in DAO enzyme activity. Identification of reduced DAO activity may improve the quality of life and treatment of symptoms in fibromyalgia patients.” states the Frontiers website when discussing Frontiers in Genetics.

DAO is an enzyme stored in tissues but primarily are found in the renal and intestinal mucosa. DAO’s purpose is to catabolize, or break down, histamine and diamines. Deficiency in DAO can create Histamine Intolerance (HIT). This can lead to neurological, gastrointestinal, and epidermal disorders.

What is recommended to assist patients in treatment is an elimination diet of high histamine foods can help patients along with recommendations of the following:

Inhibitors of mast cells would be useful in the treatment of FMS. Natural molecules could include the flavonoids, luteolin and tetramethoxyluteolin, alone or in combination with other substances selected to reduce stress. Other natural molecules could include palmitoylethanolamide, which apparently inhibits neuro-inflammation and reduces pain,” states the Frontiers in Cellular Neurology website .

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Stopping for a Moment for Lifetime Wisdom

There’s been a lot happening in my life that doesn’t happen to be anything about my chronic illnesses, however they directly have an effect on my wellness. Remember, that just because you are doing everything possible to control your illnesses, the outside world and uncontrollable influences can send you into a flare. I’m really allergic to stress, even emotional stress. How can I tell?

I have this superhuman ability to gain like 5 to 10 lbs. overnight, which my kidney specialist told me one time was absolutely impossible. No one can eat or drink that much in one day for that to just appear. No doctor had an answer. However, here I was being this fabulous super growing and shrinking woman depending on what was going on in my life. Never did we realize at that point in time, it was directly correlating with the stress that I was under. Yet here I am, rocking it, even when my body was in a peaceful state as far as illness the day before.

So, I’m going to share with you some wisdom, that has seemed to come to me over the past few years. It took a group of my family elders and myself along with an example that shortly followed that brought me to this outright wisdom.

In Parenthood and Life, “It is okay to be human, but it’s always best to be a GOOD human.”

It takes nothing to be a Good Human to Yourself. Picture Credit: Engin_Akyurt/Pixabay

There’s been many different times I’ve asked myself over my lifetime, why certain people just choose to be a bad human. Then you wonder what kind of people would raise such a human. I am naturally a curious person and a people watcher. I even studied a bit of psychology when I was young in high school prepping for college, along with any and every child development course I could and even though I didn’t follow through with any type of degree, it certainly helped me in some pretty tight spots myself.

You can meet some of the most insanely nice people and then there are just inherently bad humans, ones that steal, lie, cheat and or abuse others. However, you meet their families and parents and question “How is that even possible?” No matter the upbringing, humans are responsible and should be accountable for their own actions, and sometimes they just aren’t, and refuse to.

It’s going to directly affect you in one way or another, but you still have the choice to still be a Good Human, and act accordingly if someone does something to you that hurts you. You have control on how you react to certain situations. You do not have to bow down to their tactics, walk their path, you have the ability as a human to walk away. Even good humans, still make mistakes, choose the wrong path inadvertently, but eventually they find their way back on the right path. It takes time and it takes patience for them to catch back up, but everyone has to make their own path, and that’s okay. Like I said, it’s okay to be human.

You personally, for your well-being (and sometimes health), have to be willing to allow yourself the patience and kindness to remove yourself from that situation. You have to remember “I am human too; I have offered my help, my love, and my advice, that’s all I have to help a fellow human. I can only maintain the things that are within my control.” Whether it’s a family member, or just another human friend, sometimes you need space, and that’s okay. As a Good Human, you also have to be a GOOD HUMAN TO YOURSELF AS WELL.

Let peace reside in your heart as much as possible, to reach the best possible feeling of well-being whether you are chronically ill or not. Love and Guide where you can and forgive the ones that choose differently because it’s out of your control. –Wellness wishes from your Author

Getting back to ME!

When I hit a plateau, I search for the next step in treatment to improve. So that’s what I have been up to.

My focus and mental clarity are spot on, with the simple stuff, like taking forskolin, and Rutin, along with my antihistamines. However, I have a tendency to keep looking even when things are good, in case I missed something, then when it goes to plateau, I dig for more!

Everywhere I go, I start discussing illness in forums and groups, you get varying levels of acceptance. What I mean by that is, there are patients that accept their illnesses and want to “live with them” for the rest of their lives, and then there’s the patients constantly at “unrest”, basically not comfortable with being sick, that’s me. I’m not comfortable knowing that I have to live like this the rest of my life. I ACCEPT the fact that there is possibility I may have to, but it will never stop me from continuing to fight against it. After all, as the world turns, every day there is new science. Something new coming to the forefront. This is a revolutionary time in science and medicine.

This was a photo of myself right before I started the MTHFR journey.

Recently when studying histamine intolerance, I discovered a list of medications and things that can exacerbate histamine intolerance, and then I discovered the caveat. Even with the use of all the antihistamines I was taking and my great success with it, they BLOCK the histamines from attaching to the appropriate receptors so that you do not get symptoms. However, it does not degrade the histamine build up in your body. Which means then the histamines float around and find a new place to attach themselves to, leading to new or different symptoms.

I’m diving into that research as I go, however there had been a turn of events in my life, that turned me to studying MTHFR gene expressions, and how your body can’t methylate if you have certain genetic “SNIPS” as they refer to them. I haven’t done the testing, but I jumped on the bandwagon anyway, starting to treat myself “blindly” as is always my method since I started searching for my own health. I’m treating myself so far with Methyl folate and Vitamin B complex and Glutathione.

In one month, I no longer have to take all the antihistamines. Nothing. I have no pain, no arthritic pain, no fibromyalgia pain, and I am at full brain faculty first thing when I wake up. No longer do I sit with my caffeine for two hours waiting for my brain to clear, I’m crisp as a piece of paper first thing in the morning. I can now eat peanut butter again after 17 years, I’m pretty stoked about that. Now it doesn’t mean that I can’t have overactive histamine responses, I’m actually built to, but my body is now breaking down a great deal of histamine on its own through this methylation journey so that I’m not toxic, but if I overexpose myself, I do find myself reaching for my Cetirizine. So far, it’s only occurred twice, and only one pill for an entire day.

In our region currently, we have high tree pollen concentrations, and the farmers are out spraying, plowing and working the fields. That had put me into a migraine yesterday out of the blue, but I literally overexposed myself to more histamine than my body knew what to do with.

***NOTE: the next few links shared for Newsbreak is an affiliate link that the author can make a commission from. I appreciate the support, if you do decide to sign up!***

In my free time, I am now writing for NEWSBREAK….an app that gives you up to date information in your local area. When I’m not working on my book, I figured if I’m going to do the research to help myself, I might as well help others, so here I am. Sharing what I learn as I go, as far as fibromyalgia, Mast Cell Activation, and IBS, along with various other discoveries, and giving local information reports on barometric pressure and allergy reports in my local area.

If you feel that you would like to become a contributor or writer for your local area, it is a legitimate way to make passive income when your body is restricted in movement. I highly suggest you look into it. Just follow the link here to become a writer…. CREATOR REFERRAL.

It’s NOT IN YOUR HEAD

Mast Cell Activation Syndrome

Funny story, I came across an article that I wish I had found a few years ago. I actually wish that it had existed when I first got sick 6 plus years ago. It would have made a hell of a difference in my life.

When massive bloating happens along with a 15 pound weight gain in a week…..MCAS may be a cause. Picture Cred:Pixabay
“When a patient reports massive bloating accompanied by a 15-pound weight gain in a week, or that they can only eat a very restricted diet because they have instant horrible reactions to foods, or are experiencing weird neurological symptoms, or that they have become ultra-sensitive to a wide variety of stimuli, I immediately wonder if MCAS is at play. For some patients, the recognition and treatment of this condition have made a big difference in terms of quick symptom relief.” stated the Psychology Today website in 2019.

I remember that conversation with my Kidney Doctor, she was the only physician who tackled this complex case head on, and back in 2016/2017 Mast Cell Activation was rarely even discussed, and still hardly recognized as a condition. My condition perplexed all my physicians. If ONLY we knew then, what we know now, I may have not degraded quickly and almost lost my life. However, as I was kindly reminded last night again, I guess I never gave up the fight or gave in, I never stopped searching for answers or doing research, or using my body as a guinea pig. I was either going to get better or die. Those were my only options, and I CHOSE LIFE.

But to read this, reminds me of countless doctors that tried to get me to believe I was in a psychosomatic condition, that it was all in my head, when it was REAL.

When patients consult their primary care doctor with many seemingly random dramatic complaints affecting unrelated organ symptoms, which often feature prominent psychiatric symptoms, they are often thought to be suffering from a psychosomatic condition and told “its all in your head.” They may be sent home with a prescription for an antidepressant or anti-anxiety medication, which not only is experienced as invalidating but does not address the root cause of their symptoms.” stated the Psychology Today website .

I chose not to buy what those physicians were selling. It wasn’t in my head, and I had to trust myself on that. I chose not to be invalidated. I felt defeated several times, but never did I invalidate myself in my head or resign to believing this is just the way it was going to be. Super bummed yes, but never to the point of being willing just to give up. I sought advice, and information as much as I could hold in my head for short bouts of reading.

ANTIHISTAMINES – Receptor Blocking

H1, H2, H3, H4 Receptor Blockers

” Histamine receptors are located throughout the human body and have been classified into categories H1, H2, H3, and H4.Generally speaking, H1 receptors account for neuronal and nervous system sites, H2 are more related to stomach and digestive function, H3 receptors are found in the brain, and H4 are found in organs and bone marrow. Both H1 and H2 receptors are found in airway tissues, skin tissue, and immune cells.” Found on this website — https://www.optimusmedica.com/otc-antihistamines/#:~:text=Histamine%20receptors%20are%20located%20throughout%20the%20human%20body,H4%20are%20found%20in%20organs%20and%20bone%20marrow.

What has worked for me is in immediate flare of a critical reaction, I choose to take a Generation 1 antihistamine which is Diphenhydramine (Benedryl). However, long term use has indicated that it can cause or create dementia/Alzheimer’s or at least exasperates symptoms. I had been using Diphenhydramine for years, because the allergy shots never worked, and I’m allergic to steroids and Prednisone. So I gave that up. I had to do something.

Once I verified exactly what symptoms I was suffering from, and then figured out what receptors I needed to block, and what drugs coordinated with the ones I searched up. What worked for me was H1 and H2 blockers, which was Cetirizine (Zyrtec) and Famotidine (Pepcid AC)

Since I already was diagnosed with Fibromyalgia, and Neuropathy (even my feet were killing me and I wasn’t on them) along with my GI tract flaring, I knew that the only way for me to calm down my whole body was to block my H1 receptors and H2 receptors from antihistamine. My skin was reacting as well by the time I was diagnosed. Showers felt like whole body tattoos all at once, even the water hurt my skin like tiny needles. Each person is different, and each person will have different results and responses.

**Note: I was a guinea pig, and my primary physician was on board. He told me, “a serving suggestion is very literally a suggestion, you can take MORE of a antihistamine than what is suggested, so it took a lot of trying one , and upping the dose. My dosage is 4 times a day. 30 minutes before eating , Morning wake-up, Lunch, Dinner, and then 30 minutes before bed, to account for the histamine dump while I sleep to fight the insomnia and night sweats, when I forget to take them.

**Always check with your primary physician when taking OTC or Prescription medications. They are not pharmacy technicians, but it is important to discuss uses if you are on any other medications as well!**

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Interstitial Cystitis: Sex & Stuff

More information you probably didn’t want to know, but if you found this page, you suffer, and I understand.

For most IC sufferers, it becomes not only painful to urinate, but painful to have sexy time. No one wants the once enjoyable, to become not enjoyable anymore. There are a few things that have helped me. Since I am also a Mast Cell Activation sufferer, and allergic to most meds, and narcotics, I have had to do things naturally, find out what works, and go from there.

**Note: I have attached links to the images and titles on this page to direct link you to Amazon for your convenience. If you choose to order.

CHRONIC PAIN

Chronic pain has been the hardest thing to beat for me. I also have Fibromyalgia, and Neuropathy. I can feel EVERYTHING, and it is multiplied almost ten times by what my neurologist has tested me to be. I’ve been very fortunate to learn that RUTIN and NARIGIN can actually assist in Neurogenesis and actually help with depression-like symptoms. Always feed your brain and neurological system first. Assist them in any way you can. Most of us with systemic illnesses suffer so much that we NEED the pick me up. Being slowly tortured never helped anyone.

I highly recommend that you invest in your Nervous System, and your brain, in feeding it the bioflavonoids it needs to combat the depression, and repair inflammation in your nervous system as well!

WHAT ARE THE WHITE FLAKES IN MY URINE?

To the best of my knowledge, and what was explained to me by my own gynecologist, that is pieces of debris, normally shedding of the lining from your bladder walls. IC, is best described as we lose elasticity in the bladder wall, it shrinks, and then when it expands it tears the inner lining. We don’t reabsorb it, so it has to be expelled. ALWAYS make note that anything out of the ordinary, like physical signs of blood, odor, or discharge be communicated to your doctor promptly!

SEXY TIME – TURN Pain into Pleasure

Tips are stop using any artificial lubricants, those can quickly irritate your urethra and other parts. Essentially you have a bladder that is raw open wound, you do not want to rub salt, preservatives, or anything on an open wound on your body, so don’t do it to your bladder. Use a natural lubricant, before, during, and reapply after intercourse. Make it a standard practice, and ultimately you benefit. There are many natural lubricants, but the best effective ones are ALOE BASED. GOOD CLEAN LOVE has a pleasant smell, and works well. **Remember to diligently both men and women to empty your bladders after any intercourse during clean up.

Aloe Based Lubricants can also be mixed with Coconut Oil and frozen to make a suppository, which is widely recommended by patients. It helps with burning as well as itching. Aloe is naturally antibacterial and antifungal. Which, how lucky are we, that cold pressed coconut oil is as well! These are tried and true practices that most IC sufferers have been doing for years. With anything new, always check with your primary physician before you start or if it will work well for you!

Feel free to read my other blog post about IC: https://allergictoyourbullshit.com/2023/03/14/heartburn-from-hell/

Feeding the Brain, Stabilizing MCAS

Why the brain is necessary for all of us to function.

For me, today is a day of remembrance. In the past 30 days, I have now attended a memorial and funeral for two parents of different childhood friends, who lost their ability to remember. Alzheimer’s and Dementia have touched so many lives especially people and families that are important to me.

In retrospect it’s been almost a blessing that I suffered an illness that gave me a glimpse into my future with dementia, along with the experiences with my own family members that I had already lost. I was able to provide much needed wisdom when asked on how to navigate some of the “humane” matters with others who were already ill around me.

Until I see the MRI for myself in the near future, I am not going to glorify that the black spaces are now miraculously filled with brain matter for myself. I also will never claim a miraculous cure for anything. I do fully expect to lose my life eventually to dementia, but in the meantime, I’m going to live my life to the fullest and continue to educate myself and others as I find supplements to assist me in healing and functioning.

When researching an illness, I research how the brain operates or dysfunctions to cause said illness. Interstitial Cystitis is an actual physical dysfunction of an organ; however, the brain operates histamine reactions and releases that activate and deactivate my Mast Cell Activation Syndrome. In fact, almost ALL of my illnesses with the exception of the interstitial cystitis all tie into the brain in some way. Mast Cell Activation Syndrome, Neuropathy, Fibromyalgia, and obviously Dementia.

A little survey and digging in the Mast Cell patient group I participate in, and I sat one day and wrote down a list of 240 various different illnesses on the list (when someone polled our group on the various diagnoses’ we all had, including arthritis, and they all tie back into the brain. When I discovered that, I knew then, I had to start safeguarding my mainframe, as soon as possible, and with fierceness.

This turned me onto a host of different things that I needed to address. Cognitive Function was certainly one, and regaining my control of my memory and recovery of lost memory was another. Then regaining my energy, and focus. I found a few supplements that I simply “tried” to see if it did anything for me. The benefits had to be WORTH it, and the side effects had to be nothing or very limited for myself.

I took some of these for a few months, and started making HUGE gains, then I did the worst thing I could do, and stopped the supplements. Why you ask… because I’m the guinea pig, I’m my own test subject, and what I found was I began to degrade as quickly as I had started making improvements. In September of 2022 I stopped the supplements, and by December, I had a host of symptoms begun again, like the ADHD, the ability to not be able to clearly think, the litany of aches and pains, on top of forgetting my daily schedules. I finally admitted to my therapist what I had done at that time, and she said that it was “Invaluable” information to include in my research, but highly suggested that I begin them again. I really didn’t need them to tell me to, because that morning before I admitted to myself defeat, I may have to permanently keep myself on the Amazon Subscribe & Save program for these pills. However, I am COMPLETELY 100% totally okay with these results, it is a far car better than a ton of prescriptions from the doctors to mitigate symptoms, multiple doctor visits, and ER visits for allergic reactions and mania, or health anxiety.

My last appointment was this past Thursday, and after yet another introduction of the polyphenol Green Coffee Extract, gave me everything that I needed. Her response was to me, “You are oddly more normal, calm, controlled.” I chimed in, “I can also use BIG WORDS again!” We giggled together on that one. One day, I may ask her to actually write me an excerpt about watching my decline and then my regrowth, it’d be interesting to get it from her perspective.

My journey has been slow in progress because I am researching, and I am my own test subject, and I suggest that you do the same, research, and trust your body. You know your body best.

What has gotten me to this progress so far has been the following regimen:

RUTIN , FORSKOHLII and my H1 histamine blocker Cetirizine 10 mg along with my H2 Histamine blocker Famotidine 20mg

Now each person is different, and only respond to certain antihistamines, to find balance, sometimes you need to take more than one of each antihistamine. My balance stopped at 4 times a day, half an hour before I ingest any food, breakfast, lunch and dinner, and before bedtime. My antihistamine intake is 2 Cetirizine and 3 Famotidine every time I take a “dose”. That is what keeps me from reacting to foods, bug bites, and various other things that my mast cells deem too much histamine for the day, oh and the biggest “histamine release” is when we get sleepy and go to sleep, that is the necessity for taking them at night.

**I recommend you take a look at my blog post about Antihistamines. Take notes on your major symptoms, and start with looking at what receptor blockers are going to get rid of those reactions first.** As always, check with your physician if you are on anything. I’m not a licensed physician, this is just what got me to where I am at.

Heartburn from Hell… Interstitial Cystitis

The Disease that 30% of population may have and don’t even know it.

Discovering I had Interstitial Cystitis of the Bladder was truly an eye opener for me. It encouraged me to research, when I had the patience to read (this is a thing, especially when you are critical pain). The craziest part is there is NO TRUE DIAGNOSTIC TESTING for the disease, no known “cause” for said issues, but a multitude of symptoms. OHHHH THE HEARTBURN WAS FIERCE!

Mine was diagnosed by imaging when my gyno was all up in my junk. He took pictures, I mean, we are already there, have a handy camera, and from the outside he said it looked ANGRY, so he took some pictures from the inside. It looked like Freddy Kreuger’s face on a good day. Anyway, I’ll spare you the lunch you ate today or yesterday, and just say, it was REALLY RED and very swollen.

There is research that indicates something to the effect of our tissues losing elasticity as we age that may also cause such a condition. I can buy that as well. I highly recommend you take your Collagen! After all, Collagen is great for your joints and arthritic pain, and for the ladies we enjoy the benefits for hair and nails as well.

In real time Interstitial Cystitis, makes you feel like you have a urinary tract infection, like you have to pee ALL THE TIME, and nothing really comes out, because you constantly feel urgency. Then you dribble a little because you lose functionality when it takes over your bladder, so you got to protect yourself from weeing yourself. Most moms do anyway, those damn sneezes will send you packing your bag to the bathroom to change an entire set of clothes sometimes. Your bladder tissues get agitated, swell up, and tear the inner lining, so it’s very much like rubbing salt in your wound every single time you consume food or drink. If you are immunocompromised, have Mast Cell Activation or severe allergies, pray that you are not eating HIGH histamine foods or citric acid or night shades like bell peppers and tomatoes, there is no hell like a citric acid hitting your shredded raw bladder that I can compare it to.

Let’s get to the HEARTBURN that not even the OTC or prescription medication will touch. There are a few modern drugs on the market right now, neither did much to outweigh the need to stay on them and risk the side effects with all the other medications I was on. Insert my researching how to help myself. This pain is like no other, I couldn’t eat food! I literally would eat at like 3 p.m. in the afternoon and not be able to eat until 3 p.m. the following day because it felt like I had gastroparesis (where food doesn’t go down when it’s supposed to). The food felt like it was still sitting in my esophagus, along with ALL THE ACID. Certainly, it was going to eat a hole in my esophagus at some point.

Desperate, does not begin to describe where I was at this point. Then they hand you a list of foods you can’t eat which is basically everything in our dietary structure today in this world. Telling you to eat all organic food but nothing acidic and the list goes on and on. The one thing that got me the most is there are people who have to go into a Urinary Care Specialist and have Valium or various other pain killing medicines inserted into your bladder with loads of fluid to stretch your bladder to make it stretchy again.

I have Mast Cell Activation, I’m allergic to steroids and narcotics, and oh to boot, your insurance won’t cover a $6K procedure like that every three months. So Good Luck! I’m stubborn, I don’t listen, and I’m frugal…so I decided I could stretch my bladder on my own, after all my body naturally fills it with fluid every second of everyday, so anyone can stretch their own bladder. We can hold out the urgency and suck up the pain and go on a schedule every 2 to 3 hours, if you can hold it just a little bit longer, even better! So that’s the first thing that I did.

Yes, yes, I know, we heard this from our parents when they potty trained us, that it was not a great idea or “healthy” to hold it. I highly recommend if you do this method, you invest in those incontinence pad, panty liners, something to protect you from leaking. My determination of forcing myself onto a schedule has saved me thousands, and when I went to see the Urologist, he told me that I was in much better shape than most of his patients and to keep doing what I was doing.

The pain was a whole other level I still had to cope with. This was harder to tackle. I’m grateful however that my gyno at the time suggested to treat it like an allergic reaction to everything I consume. So that’s just what I did, insert ANTIHISTAMINES. Did you know there are 4 types of antihistamines? As long as you are taking at least and H1 and H2 antihistamine blocker daily, you are protected!

My go to H 1 antihistamine receptor blocker and H 2 antihistamine receptor blocker. Essentially, what saved me was Cetirizine, and Loratadine. With antihistamines I actually have to take 2 Cetirizine, and 3 Famotidine a day, 3 times a day. It will be how I live from now on. I also coupled it with a few more supplements suggested from the group of Mast Cell Patients had suggested work, and that were Aloe Vera Gel Capsules, and Horsetail Grass Capsules. Since 2019, I’ve purchased both of those products 8 times. I have been in a flare up at least 8 times since 2019, and it’s 2023 now. For the most part, I don’t have to take the Aloe or Horsetail unless I’m in a flare up, and when I do, I instantly start taking them three times a day, at the serving suggests on the bottle.

The Bonus to all of that, is the H1 and H2 antihistamines were literally helping my Mast Cell Activation as well, without my knowledge. I take the antihistamines even after a flare daily, that’s why the bottles that I linked here in the blog come with so many. After all, I consume so many antihistamines it seems like it’d be impossible for me to stay awake. On the contrary, I have no problem with that, since I discovered Green Coffee Extract, great polyphenols for my brain, with no jitters or crash. I can’t heart emoji that one enough.

There are two things that I have to avoid at all costs to make sure that I do not have an instant flare up. That is Carbonated Soda of any kind. I have to let the carbonation die down and drink a flat soda, it’s just easier to avoid it. The other is my first love, HOT BREWED COFFEE, Cold brew is safe. Hot brewed releases the oils in the bean, along with the histamine and mold in the bean, so instant histamine reaction. When I started the antihistamines, I was drinking a substantial amount of coffee, so I had to do something!

Anyone who suffers from severe heartburn that nothing seems to touch, male or female, I hope this may help you cure the insane pain that you suffer!

“Mom, bury me with my butt in the air, so everyone can slap me on the way out.”

The confident little man, told me at the tender age of 5.

At that moment, I knew that this child in particular, had no plans anytime soon of behaving himself. He fully intends to leave this earth in a blaze of glory. Recently he ventured out on his own at age 18 and managed to crash and burn within two weeks of leaving the homestead, but we’ve got time, he’s going to one up himself until he hits a wall. In his defense, he warned me years ago. However, I plan to fulfill his final wishes anyway I can. After all, I tell everyone that story, so as to make sure if I am gone, someone will manage to get it done, just for me, so I can laugh from the unearthly plains. (Remember, how I said, I was allergic to stress? Yes, he’s THAT child, and I am owed a slap on his behind on the way out. Haha)

I’ve spent most of my time last week remembering people, mourning a loss of someone near and dear to our family, and reorganizing my room in the process. A few weeks ago, it was a father of a bestie who was diagnosed with Alzheimer’s. This past week, a mother of a different best friend, whom had Dementia.

I honestly wish I had taken a before picture of my bedroom, but alas I didn’t. When I started falling ill, my bedroom became a little bit of a hoard, since 2014 I’ve been collecting many things. When you start to lose mental functionality, and also if you have ADHD or ADD, there is a thing called, OBJECT PERMANENCE. You may notice yourself, or even your children leaving various objects in plain view so you remember you have them so you can use them. Don’t you dare ever put anything in boxes, you’ll forget you have them and then buy more, turning into a mini hoard.

Honestly, I’m grateful for the ability to now, 1) Have the energy and focus to start tackling the “hoard”, 2) Have the ability to recognize now, why I was doing what I was doing., 3) Share this knowledge with you, or your loved ones so they can recognize an issue before it becomes a major problem.

Your loved ones, who would regularly and normally stay fairly well organized and confident in their function, start to show signs of object permanence, starting to leave things in “convenient” places so they don’t “forget” to do things or use things daily. It actually comes on pretty subtle at first. Then, there is obsessive compulsive behaviors as well coupled with the “convenient” storage of items they need daily. It’s an ugly vicious cycle to lose your cognitive function, and the family has to constantly ask themselves, “Why did they do that?” I’m telling you the why. However, don’t you dare touch their system that they have created, because there will be an argument that ensues, or at least a lot of grumbling, because they’ve lost enough cognitive or memory to remember where it was placed, once you take it out of its position to clean the house again. To be honest, they’re going to forget anyway eventually if you know they don’t use it daily, and they definitely won’t remember it at all if it’s placed in a box next to them, it’s in a box, and it is UNSEEN. “Out of sight, out of mind.”

During the process of cleaning and organizing I’ve found a treasure trove of notes that I had written myself, organized my supplements, and took up collection of EVERY SINGLE prescription bottle they had me on during my years of illness. It’s an impressive collection, and I don’t suggest you take modern medicine by the handfuls like this. Yes, there is at least two bottles that are duplicates, but that’s because it’s how it is filled, and a few creams and lotions per prescription are tossed in to balance out the multitudes of drugs my body was consuming. Essentially, I was on at least 10 medications simultaneously at all times.

I came across one of my empty bottles of Naringin as well, and I was reminded of just how far I’ve come from the days of modern medicine to healing myself naturally. Naringin deserves a Grammy or Oscar in my lineup. It’s one of the top supplements that keeps me going. To see the supplement, just follow the link here: https://amzn.to/3JCQakR

“The results of the present study concluded that naringin can effectively improve the cognitive abilities of mice with memory impairment and exert neuroprotective effects. Thus, naringin may be a promising target drug candidate for the treatment of Alzheimer’s disease.”

Meng X, Fu M, Wang S, Chen W, Wang J, Zhang N. Naringin ameliorates memory deficits and exerts neuroprotective effects in a mouse model of Alzheimer’s disease by regulating multiple metabolic pathways. Mol Med Rep. 2021 May;23(5):332. doi: 10.3892/mmr.2021.11971. Epub 2021 Mar 24. PMID: 33760152; PMCID: PMC7974313.

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Pissing my Pants Laughing

A NEW DEVICE to add Amusement to our days! Muscle Pain Relief for Fibromyalgia!

I woke up with a migraine yesterday. This is a normal thing that happens occasionally, and when I first started seeing a neurologist, he asked me if I had experienced dramatic migraines. When in fact, I hadn’t as frequently as he said I should have by the point, and condition that my brain was in. I do however wake up with the sinus headaches, and then the muscle tension migraines.

Yesterday, happened to be one of those muscle tension migraines that literally had every muscle in my shoulders tensed up that sent pain shooting into my neck and brain. I was in dire straits, that I was desperate enough to call and recruit my mom to accompany me to the massage parlor (I affectionately refer to them as “happy ending places”) to get the kinks worked out. My downfall, she had already seen her chiropractor the day before, but she texts me back with, “I’ll be there in a few minutes.” Wouldn’t you know it she showed up with this neat little device.

I’m telling you, while this thing is marked down, you literally just need to buy it, even if it’s for comedy relief. This little device, the Cervical Vertebra Massager rocked my world, and let me tell you how.

Insert a knock at my door, my mother coming to my rescue, telling me this is the best thing since sliced bread, it will save me from the pain I was enduring. This was one of those all my shoulder and back muscles were so cramped that any pain had to be better than the pain that I was enduring and pulling on all the headache muscles in my brain. I was down for anything.

She pulls out this little sticky patch with “electrodes” and then snaps this cervical device that can be recharged by USB, and slaps that puppy on my back right across the base of my neck. Now we aren’t doctors, but I’m going to tell you, we don’t play around when it comes to this kind of pain, we go to the ROOT of the problem always. She hits a button and asks, “You feel that?” “Nope, nothing.” I reply. She hits a button again and says, “how about that?” I said, “Nada.” She hits a button again and as I’m proceeding to say, “Is it on?” a jolt of electricity buckles me over, throws me forward and pops my neck in an instant, as I scream a slew of profanities, crossing my legs and praying I don’t pee all over the floor.

“What the hell you put on me, that hurts worse, than a dog shock collar!” as I am screaming, laughing, and trying not to pee myself. It’s pulsating the electricity through my muscles with fierceness. With laughter and tears in her eyes, “I’m sorry, I didn’t mean to turn it on that setting! Do you want me to shut it off? Oh my God!” as we continue to laugh until we are crying. “No, No, I’ll be fine, just leave it on, the worst is over.” The laughter continued.

I vaguely remember accusing her of damn well knowing what it would do, and that she should have videoed that mess to which we laughed some more. I’m pretty sure that if I had an Echo Show with Multiple Camera Views set up I am telling you though, that was probably the most relief I have felt from Fibromyalgia and Neuropathy pain in years. After removing the device and 12 minutes of therapy, I suggest you apply some Lidocaine of some-sort to the area, just to relieve residual pain, especially with neuropathy, so your skin doesn’t hurt. Icy Hot is a good resolve to that dilema.

Later that night, as my husband was arriving home and I was collecting the box from the counter I received a text from my mom. “Warning, Do not use it as a torture device!!!! LOL” My reply, “LMAO how’d you know? David just got home!” She just KNEW that I was going to torture my husband just for giggles. Little did I know, the joke would be on myself AGAIN before the end of the night.

Fast forward after I showed my husband the power of said device, that I had to charge it. Then I applied it to my right shoulder that was still acting up just a tad bit. Turned it on, but when the patch that I applied to my skin that holds the device in place came up a little, I reached back to readjust while the device was on, and my finger got stuck on the pad electrode, and I was grounded in a complete circle, so my arm was flexing glued to the pad, sending and electrode from my shoulder to my fingertips and back through, leaving me screaming, “Help, Help, Help me David, shut it off!”

I highly advise, never use this device without an extra pair of hands handy to shut off that button in places you can’t reach. If you need new sticky patches, you can order those too! I’m telling you, I’m the test subject here, and if it’s working for my mom, and myself, as long as you have assistance during use. You got to have this in your artillery. My hubby also pointed out, this thing is powerful enough, if you were brave enough to apply it to your abdomen, it’d probably give you a heller ab workout as well, but that’s not what it’s made for.

***NOTE: There are two versions to this Massager, the battery operated and the USB charged one. Battery operated has less jolt and less power to it, however, USB charging is what my mom used on me. We have both, so for a tame less shocking experience I suggest battery operated, but for those massive muscle cramps, only USB will do for DEEP TISSUE massage.